The treatment of anogenital extramammary Paget's disease as part of a multidisciplinary approach: The use of Mohs surgery moat method with CK7
| Autor: | Kevin R. Brough, Nahid Y. Vidal, Sama K. Carley |
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| Rok vydání: | 2021 |
| Předmět: |
High rate
medicine.medical_specialty business.industry medicine.medical_treatment Margins of Excision Dermatology medicine.disease Mohs Surgery Perineum Extramammary Paget's disease Micrographic surgery Paget Disease Extramammary Multidisciplinary approach Anogenital region medicine Mohs surgery Humans business |
| Zdroj: | International journal of dermatologyReferences. 61(2) |
| ISSN: | 1365-4632 |
| Popis: | Although most cases of extramammary Paget's disease (EMPD) are localized to the intraepidermal, the extensive subclinical extension can lead to high rates of marginal recurrence with wide local excisions and topically destructive treatments. Recurrence rates of EMPD treated with Mohs micrographic surgery (MMS) without immunohistochemical staining are better but variable. Here, we describe our multidisciplinary approach for treating large EMPD tumors of the anogenital region involving critical anatomy using MMS for peripheral margin clearance (moat method) and intraoperative CK7 immunostaining. Our clinical pearls for the management of anogenital EMPD are based on 53 multidisciplinary cases treated at the author's institution between 2014 and 2020. |
| Databáze: | OpenAIRE |
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