Effects of chemical combinations on the parthenogenetic activation of mouse oocytes

Autor: Jun‑Ling Gao, Bao‑Sheng Han
Rok vydání: 2012
Předmět:
Zdroj: Experimental and Therapeutic Medicine
ISSN: 1792-0981
Popis: The aim of this study was to identify an optimal method for the parthenogenetic activation of mouse oocytes. Ethanol (EH), strontium chloride (SrCl2) and ionomycin calcium salt were each combined with cytochalasin B to induce the parthenogenetic activation of CD-1® mouse oocytes. Among the EH combination groups, the blastocyst formation and hatching rates of the group that was activated with EH and CB for 5 min were significantly higher compared with those of the groups that were activated for 7 and 10 min (P
Databáze: OpenAIRE