Glycated Hemoglobin Detection in Clinical Blood Samples by Using CMOS Poly-silicon Sub-micron Wire Biosensor
| Autor: | Chih-Ting Lin, I.-Shun Wang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Measurement method
Materials science 010401 analytical chemistry Analytical chemistry 030209 endocrinology & metabolism General Medicine 01 natural sciences Functional system 0104 chemical sciences 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine CMOS chemistry Hba1c test Diabetes monitoring Glycated hemoglobin Biosensor Limited resources Engineering(all) Biomedical engineering |
| Zdroj: | Procedia Engineering. 168:121-124 |
| ISSN: | 1877-7058 |
| Popis: | This paper presents hemoglobin (Hb) and glycated hemoglobin (HbA1c) in clinical blood samples detection by a poly-silicon sub-micron wire (poly-Si SW) biosensor. HbA1c examination has been a better method in long-term diabetes monitoring without day-to-day glucose level fluctuations. Currently, HbA1c test need to be performed in laboratory or hospital because of complicated operation and the need of well-trained operator. This limits its applications in homecare application and resource limited area. The sensing results of poly-Si SW were compared to the standard Hb and HbA1c measurement methods and showed comparable results. Compared with conventional examination methods, using CMOS poly-Si SW biosensor can economize the cost of diagnoses and easily integrate with different functional systems. Based on our previous results, our work could potentially be applied for next generation healthcare application. |
| Databáze: | OpenAIRE |
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