Diabetic ketoacidosis in acromegaly; a rare complication precipitated by corticosteroid use
| Autor: | Jeremy Weiss, Mathis Grossmann, Elif I Ekinci, Sofianos Andrikopoulos, Jeffrey D Zajac, Anna J Wood |
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| Rok vydání: | 2017 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Pediatrics Diabetic ketoacidosis Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Diabetic Ketoacidosis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Adrenal Cortex Hormones Diabetes mellitus Acromegaly Internal Medicine medicine Humans Insulin-Like Growth Factor I business.industry Insulin General Medicine medicine.disease Pasireotide Recombinant Proteins Surgery Ketoacidosis chemistry Pegvisomant Female Complication business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Diabetes research and clinical practice. 134 |
| ISSN: | 1872-8227 |
| Popis: | Diabetic ketoacidosis has been described in the literature as a rare possible initial presentation of acromegaly before a diagnosis of acromegaly is eventually made. Indeed, diabetic ketoacidosis is a recognised complication of acromegaly. There are a number of factors that can predispose patients with acromegaly to diabetes as well as to diabetic ketoacidosis. These include high levels of growth hormone and insulin-like growth factor 1 in acromegaly and the effect on glycaemia by medications used in the management of acromegaly. Ketoacidosis has been described in patients with acromegaly even without the presence of an underlying autoimmune diabetes. Patients with acromegaly and ketoacidosis often respond to treatment and may not require long-term insulin. |
| Databáze: | OpenAIRE |
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