Developmental trajectories of hierarchical visuo-spatial processing in fragile X syndrome and ASD: Within- and cross-syndrome variability
| Autor: | Carrie Ballantyne, Christie Ballantyne, Maria Nunez |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty genetic structures Adolescent Autism Spectrum Disorder Audiology behavioral disciplines and activities Developmental psychology Cohort Studies 03 medical and health sciences 0302 clinical medicine Child Development Spatial Processing mental disorders Developmental and Educational Psychology medicine Humans 0501 psychology and cognitive sciences Child 05 social sciences Case-control study medicine.disease Child development Fragile X syndrome Clinical Psychology Autism spectrum disorder Case-Control Studies Fragile X Syndrome Cross syndrome Childhood Autism Rating Scale Autism Female Psychology 030217 neurology & neurosurgery 050104 developmental & child psychology Cohort study |
| Zdroj: | Research in developmental disabilities. |
| ISSN: | 1873-3379 |
| Popis: | Background/aims Despite the advances in understanding visuo-spatial processing in developmental disorders such as ASD and fragile X syndrome (FXS), less is known about the profile of those with a comorbid diagnosis, or the role of within-disorder disparities between individuals across the ASD spectrum. Methods and procedures Using a developmental trajectory approach, we tested 5 groups of children: Typically developing, FXS, FXS + ASD, ASD individuals who had low-moderate symptoms (HFA) and ASD individuals who had severe symptoms (LFA). Symptoms of ASD were assessed using the Childhood Autism Rating Scale: CARS and hierarchical visuo-spatial processing was assessed using the Navon task. Outcomes and results Crucially, results differed between HFA and LFA participants. Furthermore, the pattern of results differed between those who had a diagnosis of FXS only and FXS + ASD. Poorer performance within the FXS groups and the group who are low functioning on the ASD spectrum indicated a delayed developmental rate compared to typical controls. Conclusions and implications This study showed that diagnosis and severity of symptoms are indicative of differences in visuo-spatial processing styles. It is important that heterogeneity within FXS and ASD populations are considered in subsequent studies and look beyond diagnostic group differences. |
| Databáze: | OpenAIRE |
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