Boron Neutron Capture Therapy Study of 10B Enriched Nanostructured Boron Carbide Against Cervical Cancer and Glioblastoma Cell Line
| Autor: | Hiroyuki Nakamura, Ramovatar Meena, Paviter Singh, Fumiko Nakagawa, Manjot Kaur, Akshay Kumar, Minoru Suzuki |
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| Rok vydání: | 2020 |
| Předmět: |
inorganic chemicals
Materials science Nanochemistry chemistry.chemical_element 02 engineering and technology Boron carbide 010402 general chemistry 01 natural sciences Biochemistry HeLa chemistry.chemical_compound General Materials Science Boron Isotope biology Radiochemistry Hexagonal phase General Chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics biology.organism_classification Neutron temperature 0104 chemical sciences Neutron capture chemistry 0210 nano-technology |
| Zdroj: | Journal of Cluster Science. 32:221-225 |
| ISSN: | 1572-8862 1040-7278 |
| DOI: | 10.1007/s10876-020-01773-z |
| Popis: | Boron carbide enriched with 10B isotope (10B4C) was synthesized by simple and low cost solvothermal method. Structural, morphological and optical analysis has been done. Hexagonal phase of the synthesized material show emission in visible region and makes it a promising material for cancer diagnosis. Cytotoxicity analysis has been done to analyze its suitability for biomedical applications. Boron neutron capture therapy (BNCT) has been performed using thermal neutron source in comparison to clinically studied compound on tumor cell lines (HeLa and U-87MG). |
| Databáze: | OpenAIRE |
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