Efficacy and safety of intralesional triamcinolone acetonide in the treatment of chronic hand eczema
| Autor: | Saiful Islam Bhuiyan, Md. Shahidullah Sikder, Harashit Kumar Paul, A. S. M. Zakaria, Tasnuva Ashraf, Kaniz Shahali Reza Snigdha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Triamcinolone acetonide business.industry General Arts and Humanities lcsh:R Eczema lcsh:Medicine medicine.disease Hand Dermatology Group B Intralesional Clinical trial Hand eczema Clobetasol Diabetes mellitus Chronic hand eczema Medicine Clobetasol propionate business medicine.drug |
| Zdroj: | Bangabandhu Sheikh Mujib Medical University Journal, Vol 10, Iss 3 (2017) |
| ISSN: | 2224-7750 2074-2908 |
| Popis: | This randomized controlled clinical trial was conducted to assess the efficacy and safety of intralesional triamcinolone acetonide in the treatment of chronic hand eczema comparing with topical clobetasol propionate. A total 60 patients of chronic hand eczema were recruited in the study. Thirty patients (Group A) were treated with intralesional triamcinolone acetonide and the rest 30 (Group B) with topical clobetasol propionate. Severity and improvement were assessed using Hand Eczema Severity Index (HECSI) score. The patients of both groups were followed up at 4th week and 12th week. In Group A, median HECSI score at baseline, 4th week and 12th week were 3, 20 and 20 respectively; whereas these scores were 54, 10 and 8 in Group B. In both groups, HECSI score was decreased gradually but the rate was higher in Group B than Group A (p0.05). The result of this study demonstrates that intralesional triamcinolone acetonide is effective and safe in treating chronic hand eczema but less effective than the topical clobetasol. |
| Databáze: | OpenAIRE |
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