Incidence of anaphylactic reactions after propofol administration in dogs
| Autor: | Tadashi Sano, Akiyoshi Murakami, Misao Terada, Sadaharu Ono, Tomoko Ishida, Mamoru Onuma |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Allergy 040301 veterinary sciences Anesthesia General anesthesia Immunoglobulin E 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound Dogs 0302 clinical medicine Lecithins Animals Hypnotics and Sedatives Medicine Dog Diseases Egg Hypersensitivity Adverse effect Anaphylaxis Propofol Retrospective Studies immunoglobulin-E Full Paper propofol-induced anaphylaxis General Veterinary biology business.industry Incidence 04 agricultural and veterinary sciences Perioperative medicine.disease histamine Soybean Oil 030228 respiratory system chemistry Isoflurane Anesthesia dog biology.protein Surgery Female business Anesthetics Intravenous Histamine medicine.drug |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.16-0550 |
| Popis: | Propofol is an anesthetic agent suspended in an emulsion system that includes egg yolk lecithin and soybean oil, because of which, there is concern about the use of propofol in patients allergic to these substances. We examined the association between propofol administration and incidence of adverse events in dogs with allergy to egg yolk lecithin and soybean oil. On the basis of the findings of an allergen-specific immunoglobulin E (IgE) test, 14 dogs with high levels (high-IgE group) and 7 dogs with low levels (normal-IgE group) of IgE were selected. Following intravenous administration of propofol, the incidence of anaphylactic reactions and plasma histamine concentrations under general anesthesia maintained with isoflurane throughout surgery were compared between the two groups. The frequency of anaphylactic reactions and plasma histamine concentrations were compared by the chi-square test and Student t-test, respectively. The statistical significance for both tests was set at P |
| Databáze: | OpenAIRE |
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