Alterations in cell cycle dynamics in human endothelium cell culture infected with influenza virus

Autor:	Prochukhanova Ar, A. V. Nazarova, O. G. Lublinskaya, Azarenok Aa, I. N. Zhilinskaya, V. V. Zenin
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	A549 cell endothelial cell culture Endothelium Contact inhibition Cell Biology Biology Cell cycle Virology Virus Article influenza virus Nocodazole chemistry.chemical_compound medicine.anatomical_structure chemistry Cell culture medicine cell cycle S phase
Zdroj:	Cell and Tissue Biology
ISSN:	1990-5203 1990-519X
Popis:	The cell cycle of endothelium EAhy 926 cell culture infected with influenza virus has been studied. Cytometric analysis of cell culture synchronized by contact inhibition revealed the elongation of the S phase of the cell cycle in EAhy 926 cells under the influence of influenza virus. This result was shown in an EAhy 926 culture infected with influenza virus and treated with nocodazole. Comparison of a lung carcinoma A549 cell line in which influenza virus causes G0/G1 arrest and of an endothelial EAhy 926 cell line in which the same infection leads to S-phase elongation allows it to be suggested that different effects of influenza virus on cell cycle dynamics depend on the origin of infected cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e86652f910f2c7ce1ddb0397ff5c712 http://europepmc.org/articles/PMC7089363 Zobrazit plný text záznamu Full text from SpringerLink