Biological monitoring of occupational ethylbenzene exposure by means of urinalysis for un-metabolized ethylbenzene

Autor: Haruhiko Sakurai, Masayuki Ikeda, Toshio Kawai
Rok vydání: 2019
Předmět:
Zdroj: Industrial Health
ISSN: 1880-8026
0019-8366
DOI: 10.2486/indhealth.2018-0170
Popis: This study aimed to examine quantitative relation between ethylbenzene (EB) in air (EB-A) and un-metabolized EB in urine (EB-U) for biological monitoring of occupational EB exposure by urinalysis for EB. In total, 49 men in furniture production factories participated in the study. Time-weighted average EB-A was monitored by diffusive sampling. Urinalysis for EB was conducted by head-space gas-chromatography with end-of-shift samples. Data were subjected to regression analysis for statistical evaluation. A geometric mean (GM) and the maximum (Max) EB-A levels were 2.1 and 45.5 ppm, respectively. A GM and the Max for EB-U (observed values) were 4.6 and 38.7 µg/l. A significant linear correlation was observed. The regression equation was Y=3.1+0.73X where X is EB-A (ppm) and Y is EB-U (μg/l) (r=0.91, p
Databáze: OpenAIRE