Phagocytic uptake of synthetic particles in blood leukocytes of fetal and newborn athymic nude mice
| Autor: | V. Větvička, J. Chalupná, L. Fornůsek, M. Holub |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Pathology medicine.medical_specialty Phagocytosis Immunology Mice Nude Receptors Fc Andrology Mice Nude mouse Pregnancy Athymic Nude Mouse Leukocytes medicine Animals Immunology and Allergy Receptor Fetus biology Fetal Blood biology.organism_classification In vitro Animals Newborn Gestation Female |
| Zdroj: | Immunology Letters. 8:93-96 |
| ISSN: | 0165-2478 |
| DOI: | 10.1016/0165-2478(84)90057-9 |
| Popis: | Monocytes are the main phagocytic element in the blood of fetal mice; monocytes of athymic nude mouse fetuses (gestation days 17–20) ingest in vitro, in full blood, significantly more synthetic (HEMA) particles than the monocytes of their euthymic littermates. Blood leukocytes of athymic fetuses also bear much higher densities of Fc receptors for IgG 2B . The differences in phagocytic uptake in blood leukocytes disappear and the differences in Fc(IgG 2B ) receptors decrease at postnatal days 2 and 4. |
| Databáze: | OpenAIRE |
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