Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties
| Autor: | Gianfranco Peluso, Menotti Calvani, Paola Benatti, Raffaella Nicolai |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
chemistry.chemical_classification
Regulation of gene expression Cell signaling Nutrition and Dietetics Transcription Genetic Eicosanoid metabolism Medicine (miscellaneous) Nutritional Status Lipid metabolism Biology Dietary Fats Eicosanoid chemistry Biochemistry Dietary Fats Unsaturated Gene Expression Regulation Chronic Disease Fatty Acids Unsaturated Animals Humans lipids (amino acids peptides and proteins) Epigenetics Transcription factor Polyunsaturated fatty acid |
| Zdroj: | Journal of the American College of Nutrition. 23(4) |
| ISSN: | 0731-5724 |
| Popis: | Dietary polyunsaturated fatty acids (PUFA) have effects on diverse physiological processes impacting normal health and chronic diseases, such as the regulation of plasma lipid levels, cardiovascular and immune function, insulin action and neuronal development and visual function. Ingestion of PUFA will lead to their distribution to virtually every cell in the body with effects on membrane composition and function, eicosanoid synthesis, cellular signaling and regulation of gene expression. Cell specific lipid metabolism, as well as the expression of fatty acid-regulated transcription factors, likely play an important role in determining how cells respond to changes in PUFA composition. This review will focus on recent advances on the essentiality of these molecules and on their interplay in cell physiology, leading to new perspective in different therapeutic fields. |
| Databáze: | OpenAIRE |
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