MR-guided motion-corrected PET image reconstruction for cardiac PET-MR
| Autor: | Radhouene Neji, Camila Munoz, Sam Ellis, Julia A. Schnabel, Stephan G. Nekolla, Andrew J. Reader, Claudia Prieto, Teresa Vitadello, René M. Botnar, Karl P. Kunze |
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| Předmět: |
Motion compensation
business.industry Image quality Computer science media_common.quotation_subject Noise reduction Iterative reconstruction ddc Neuroimaging Cardiac PET Image noise Contrast (vision) Radiology Nuclear Medicine and imaging Computer vision Artificial intelligence business media_common |
| Zdroj: | King's College London |
| Popis: | Simultaneous PET-MR imaging has shown potential for the comprehensive assessment of myocardial health from a single examination. Furthermore, MR-derived respiratory motion information has been shown to improve PET image quality by incorporating this information into the PET image reconstruction. Separately, MR-based anatomically guided PET image reconstruction has been shown to perform effective denoising, but this has been so far demonstrated mainly in brain imaging. To date the combined benefits of motion compensation and anatomical guidance have not been demonstrated for myocardial PET-MR imaging. This work addresses this by proposing a single cardiac PET-MR image reconstruction framework which fully utilises MR-derived information to allow both motion compensation and anatomical guidance within the reconstruction. Methods: Fifteen patients underwent a 18F-FDG cardiac PET-MR scan with a previously introduced acquisition framework. The MR data processing and image reconstruction pipeline produces respiratory motion fields and a high-resolution respiratory motion-corrected MR image with good tissue contrast. This MR-derived information was then included in a respiratory motion-corrected, cardiac-gated, anatomically guided image reconstruction of the simultaneously acquired PET data. Reconstructions were evaluated by measuring myocardial contrast and noise and compared to images from several comparative intermediate methods using the components of the proposed framework separately. Results: Including respiratory motion correction, cardiac gating, and anatomical guidance significantly increased contrast. In particular, myocardium-to-blood pool contrast increased by 143% on average (p |
| Databáze: | OpenAIRE |
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