A randomized clinical trial of the effects of saphenous and perforating veins radiofrequency ablation on venous ulcer healing (VUERT trial)
| Autor: | Jorgete Barreto dos Santos, Walter Campos, Pedro Puech-Leão, Erasmo Simão da Silva, Nelson De Luccia, Igor Rafael Sincos, Juliana Puggina, Rina Maria Pereira Porta, F. Collares |
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| Rok vydání: | 2020 |
| Předmět: |
Ulcer healing
Radiofrequency Ablation Wound Healing medicine.medical_specialty business.industry Radiofrequency ablation Endovenous ablation General Medicine medicine.disease Venous leg ulcer Varicose Ulcer law.invention Surgery Treatment Outcome Randomized controlled trial law Humans Medicine Saphenous Vein Prospective Studies Perforating veins Cardiology and Cardiovascular Medicine business Ulcer |
| Zdroj: | Phlebology: The Journal of Venous Disease. 36:194-202 |
| ISSN: | 1758-1125 0268-3555 |
| DOI: | 10.1177/0268355520951697 |
| Popis: | Objectives To investigate whether radiofrequency endovenous ablation (RFA) of saphenous and perforating veins increases venous leg ulcer (VLU) healing rates and prevents ulcer recurrence. Method This prospective, open-label, randomized, controlled, single-center trial recruited 56 patients with VLU divided into: compression alone (CR, N = 29) and RFA plus compression (RF, N = 27). Primary endpoints were ulcer recurrence rate at 12 months; and ulcer healing rates at 6, 12, and 24 weeks. Secondary endpoints were ulcer healing velocity; and Venous Clinical Severity Score (VCSS). Results Recurrence was lower in the RF group (p Conclusions RFA plus compression is an excellent treatment for VLU because of its safety, effectiveness, and impact on ulcer recurrence reduction and clinical outcome. Registration: Clinicaltrials.gov, NCT03293836, clinicaltrials.gov. |
| Databáze: | OpenAIRE |
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