Self-reported Disability in Patients with Inflammatory Bowel Disease Largely Determined by Disease Activity and Illness Perceptions
| Autor: | Have, M. van der, Fidder, H.H., Leenders, M., Kaptein, A.A., Valk, M.E. van der, Bodegraven, A.A. van, Dijkstra, G., Jong, D.J. de, Pierik, M., Ponsioen, C.Y., Meulen-de Jong, A.E. van der, Woude, C.J. van der, Meeberg, P.C. van de, Romberg-Camps, M.J.L., Clemens, C.H.M., Jansen, J.M., Mahmmod, N., Bolwerk, C.J.M., Vermeijden, J.R., Siersema, P.D., Oldenburg, B., COIN Study Grp, Dutch Initiative Crohn Colitis |
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| Přispěvatelé: | Gastroenterology & Hepatology, Interne Geneeskunde, Health promotion, RS: NUTRIM - R2 - Gut-liver homeostasis, Gastroenterology and hepatology, CCA - Innovative therapy, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Groningen Institute for Organ Transplantation (GIOT), Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology |
| Rok vydání: | 2015 |
| Předmět: |
Male
Ulcerative INTERNATIONAL CLASSIFICATION Disease Severity of Illness Index Inflammatory bowel disease Crohn Disease QUALITY-OF-LIFE Surveys and Questionnaires Immunology and Allergy Medicine Prospective Studies Non-U.S. Gov't PREDICTORS Prospective cohort study Response rate (survey) Research Support Non-U.S. Gov't Gastroenterology determinants Middle Aged Colitis Prognosis Ulcerative colitis CROHNS-DISEASE ULCERATIVE-COLITIS Rheumatoid arthritis Female HEALTH IBD disability index Adult medicine.medical_specialty QUESTIONNAIRE Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0] Research Support VALIDATION Quality of life (healthcare) Internal medicine Severity of illness Journal Article health care costs Humans Disabled Persons illness perceptions business.industry medicine.disease digestive system diseases RHEUMATOID-ARTHRITIS WORK DISABILITY Quality of Life Physical therapy Colitis Ulcerative Perception Self Report business Follow-Up Studies |
| Zdroj: | Inflammatory Bowel Diseases, 21(2), 369-377. Oxford University Press Inflammatory Bowel Diseases, 21(2), 369-377. LIPPINCOTT WILLIAMS & WILKINS Inflammatory Bowel Diseases, 21(2), 369-377. John Wiley and Sons Inc. Inflammatory Bowel Diseases, 21(2), 369-377 Inflammatory bowel diseases, 21(2), 369. John Wiley and Sons Inc. ten Have, M, Fidder, H H, Leenders, M, Kaptein, A A, van der Valk, M E, van Bodegraven, A A, Dijkstra, G, de Jong, D J, Pierik, M, Ponsioen, C Y, de Jong, A, van der Woude, C J, van de Meeberg, P C, Romberg-Camps, M J L, Clemens, C H M, Jansen, J M, Mahmmod, N, Bolwerk, C J M, Vermeijden, J R, Siersema, P D & Oldenburg, B 2015, ' Self-reported Disability in Patients with Inflammatory Bowel Disease Largely Determined by Disease Activity and Illness Perceptions ', Inflammatory Bowel Diseases, vol. 21, no. 2, pp. 369-377 . https://doi.org/10.1097/MIB.0000000000000278 Inflammatory Bowel Diseases, 21, 369-77 Inflammatory Bowel Diseases, 21, 2, pp. 369-77 Inflammatory bowel diseases, 21(2), 369-377. John Wiley and Sons Inc. |
| ISSN: | 1078-0998 |
| Popis: | Item does not contain fulltext BACKGROUND: The inflammatory bowel disease (IBD) disability index has recently been introduced to measure patients' physical, psychological, familial, and social limitations associated with IBD. We assessed factors related to self-reported disability and the relationship between disability and direct health care costs. METHODS: A large cohort of patients with Crohn's disease (CD) and ulcerative colitis (UC) was prospectively followed for 2 years by 3 monthly web-based questionnaires. At 2 years, patients completed the IBD disability index, with lower score indicating more disability. Linear regression analysis was used to examine the impact of demographics, clinical characteristics, and illness perceptions on self-reported disability. Trends in direct health care costs across the disability severity groups minimal, mild, moderate, and severe, were tested. RESULTS: A total of 554 patients with CD and 424 patients with UC completed the IBD disability index (response rate, 45%). Both clinical characteristics and illness perceptions significantly contributed to self-reported disability (45%-47%, P = 0.000 and 8%-12%, P = 0.000, respectively). Patients with CD scored lower on the self-reported IBD disability index than patients with UC (0.255 versus 3.890, P < 0.000), indicating more disability in patients with CD. Factors independently associated with higher self-reported disability rates were increased disease activity, illness identity (higher number of symptoms attributed to IBD), and stronger emotional response. Disease duration and disease phenotype were not associated with self-reported disability. Direct health care costs increased with the worsening of self-reported disability (P = 0.000). CONCLUSIONS: More disability was reported by patients with CD than by UC. Self-reported disability in IBD was mainly determined by clinical disease activity and illness perceptions but not by disease duration or disease phenotype. |
| Databáze: | OpenAIRE |
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