Use of Autologous Leucocyte- and Platelet-Rich Plasma (L-PRP) in the Treatment of Aural Hematoma in Dogs
| Autor: | Eva Spada, Roberta Perego, Elena Moneta, Luciana Baggiani, Daniela Proverbio |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
General Veterinary treatment business.industry Veterinary medicine aural hematoma Complete resolution Article Surgery Clinical trial leucocyte- and platelet-rich plasma dog Otitis Platelet-rich plasma SF600-1100 medicine medicine.symptom business Aural hematoma Whole blood |
| Zdroj: | Veterinary Sciences, Vol 8, Iss 172, p 172 (2021) Veterinary Sciences; Volume 8; Issue 9; Pages: 172 Veterinary Sciences |
| ISSN: | 2306-7381 |
| Popis: | Leukocyte- and platelet-rich plasma (L-PRP) can accelerate the healing process by providing increased concentrations of platelet-derived growth factors. The objective of this study was to evaluate the clinical effect of L-PRP in the treatment of canine aural hematomas associated with otitis externa. Twenty mL of citrated whole blood was collected from each of the 17 dogs included and autologous L-PRP was produced. The aural hematoma was drained and 0.5–1 mL of L-PRP was injected. The dogs were examined weekly until 7 days after complete clinical healing. A final clinical follow-up was performed 6 weeks after the first treatment with L-PRP. If there was recurrence of the aural hematoma at the first follow-up, the treatment was repeated. In total, 2/17 cases were lost after the first follow-up. In 5/17 dogs, a short-term recurrence occurred. In 12/15 cases, complete clinical resolution was achieved with a single L-PRP application (Group A1) and in 3/15 with two treatments (Group A2). The mean time to complete clinical resolution was 16 ± 8.7 days (A1) and 23.3 ± 4 days (A2), respectively. No side effects were reported. The in situ administration of autologous L-PRP resulted in a complete resolution of the aural hematoma in all dogs that completed the clinical trial. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|