Observations on the status of collagen in human gingiva

Autor: E. Aas, S.D. Schultz-Haudt
Rok vydání: 1960
Předmět:
Zdroj: Archives of oral biology. 2
ISSN: 0003-9969
Popis: The amounts of total, soluble and insoluble collagens have been determined in clinically normal and chronically inflamed human gingiva, and in hyperplastic gingiva from patients receiving sodium diphenylhydantoin. The results suggest that the histological disappearance of the collagenous fibre bundles in chronic gingivitis may be due to a disorganization of the fibre bundles along with a deficient precipitation of the soluble precursors into the insoluble fibres rather than to a greatly increased rate of collagen breakdown. In hyperplasia of the gingiva, as induced by sodium diphenylhydantoin, collagen appears to be metabolized at a reduced rate, rather than being formed at an accelerated rate. On the basis of the results, suggestions are made with regard to a new approach for evaluating the influence of “endogenous predisposing factors” in chronic periodontitis.
Databáze: OpenAIRE