Differential effects of neurotoxin-induced lesions of the basolateral amygdala and central nucleus of the amygdala on lithium-induced conditioned disgust reactions and conditioned taste avoidance
| Autor: | Linda A. Parker, Shadna A. Rana |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Taste Conditioning Classical Amygdala Rats Sprague-Dawley Behavioral Neuroscience chemistry.chemical_compound Basal ganglia Avoidance Learning Excitatory Amino Acid Agonists medicine Animals Neurotoxin Saccharin Central nucleus of the amygdala Association Learning Nausea Disgust Rats Flavoring Agents medicine.anatomical_structure nervous system chemistry Lithium Chloride Psychology Neuroscience psychological phenomena and processes Basolateral amygdala |
| Zdroj: | Behavioural Brain Research. 189:284-297 |
| ISSN: | 0166-4328 |
| DOI: | 10.1016/j.bbr.2008.01.005 |
| Popis: | When rats are intraorally exposed to saccharin solution that has previously been paired with lithium chloride (LiCl), they display Pavlovian conditioned disgust reactions. When exposed to LiCl-paired saccharin solution by bottle, they display suppressed instrumental approach to the bottle resulting in suppressed consumption. The present experiments demonstrated that while neither neurotoxin-induced lesions of the basolateral amygdala (BLA) nor the central nucleus of the amygdala (CeA) attenuated the display of Pavlovian conditioned disgust reactions, lesions of the BLA (but not the CeA) attenuated instrumental conditioned avoidance of the taste. The results are discussed in light of current models of the role of the amygdala in aversive learning. |
| Databáze: | OpenAIRE |
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