Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge
| Autor: | A Wasserman, O. Friedgut, Z. Oved, J. Brenner, Daniel Elad, M Haimovitz, M Bellaiche, V. Bumbarov, Emanuel Gross, Yehuda Stram, Hagai Yadin |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Lumpy Skin Disease Genome Viral Beef cattle Vaccines Attenuated Lumpy skin disease Immunity medicine Potency Animals Israel Skin Sheeppox General Veterinary General Immunology and Microbiology business.industry Viral Vaccine Public Health Environmental and Occupational Health Viral Vaccines medicine.disease Lumpy skin disease virus Vaccination Infectious Diseases Immunology Molecular Medicine Cattle Female business |
| Zdroj: | Vaccine. 27(10) |
| ISSN: | 0264-410X |
| Popis: | The ultimate goal of a vaccine is to protect vaccinated animals against re-exposure to the same pathogen and provide sterile immunity. However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006-2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect