On the Polymorphism of Griseofulvin: Identification of Two Additional Polymorphs
Autor: | Aurélien Mahieu, Mark D. Eddleston, William Jones, Jean-François willart, Marc Descamps, Emeline Dudognon, Florence Danede |
---|---|
Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Journal of Pharmaceutical Sciences. 102:462-468 |
ISSN: | 0022-3549 |
DOI: | 10.1002/jps.23349 |
Popis: | In this paper, we present an investigation of the polymorphism of griseofulvin. In addition to the only reported crystalline form (form I), two new polymorphic forms (II and III) have been identified and characterized by differential scanning calorimetry and powder X-ray diffraction. Reasons why these two polymorphs were isolated during the present study, but not detected during the numerous previous studies on this drug, are also discussed. |
Databáze: | OpenAIRE |
Externí odkaz: |