Long-term sequelae of Pelvis irradiation: Histological and microradiographical study of a femoral head

Autor:	Catherine Nyssen-Behets, R. Dambrain, Serge Orloff, Olivier Delaere, Antoine Dhem, J.C. Autrique
Rok vydání:	1991
Předmět:	Pathology medicine.medical_specialty business.industry Osteonecrosis Femur Head General Medicine Anatomy Middle Aged Pelvis Bone remodeling Resorption Radiography Femoral head medicine.anatomical_structure Rheumatology medicine Humans Osteoporosis Female business
Zdroj:	Clinical Rheumatology. 10:206-210
ISSN:	1434-9949 0770-3198
DOI:	10.1007/bf02207666
Popis:	Despite the lack of radiological signs, a femoral head showed histological and microradiographical features of osteonecrosis, 54 years after massive irradiation of the right hip. Intertrabecular spaces were invaded by connectivo-vascular tissue with focal accumulation of mast cells, and several resorption foci were filled with mononucleated cells. Moreover, all the microradiographs showed peculiar hypercalcified lines, sometimes containing empty osteocytic lacunae, the origin of which is difficult to precise. This study suggests that massive irradiation of weight-bearing epiphyses may be responsible for particularly long-term hypovascularity, osteonecrosis and disturbed bone remodeling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e55511fc8b8faa79284e3e853ea102f https://doi.org/10.1007/bf02207666 Zobrazit plný text záznamu Full text from SpringerLink