Successful thyroid tissue ablation as defined by a negative whole-body scan or an undetectable thyroglobulin: a comparative study
| Autor: | Maroun Karam, Ayesha Cheema, Paul J. Feustel, C Richard Goldfarb, Eric S Postal |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Statistics as Topic Urology Sensitivity and Specificity Thyroglobulin Whole-Body Counting Iodine Radioisotopes Humans Medicine Radiology Nuclear Medicine and imaging Thyroid Neoplasms Radionuclide Imaging Thyroid cancer Aged Aged 80 and over Univariate analysis business.industry Thyroid Thyroidectomy Reproducibility of Results General Medicine Odds ratio Middle Aged Prognosis Ablation medicine.disease Confidence interval Surgery Treatment Outcome medicine.anatomical_structure Neoplasm Recurrence Local Radiopharmaceuticals business |
| Zdroj: | Nuclear Medicine Communications. 26:331-336 |
| ISSN: | 0143-3636 |
| DOI: | 10.1097/00006231-200504000-00005 |
| Popis: | BACKGROUND: Successful thyroid tissue ablation of patients with well-differentiated thyroid cancer can be defined by a negative whole-body scan (WBS) and/or an undetectable thyroglobulin (Tg). Variables associated with success are poorly understood. Tg measurement, although more sensitive than WBS, has not been firmly established as the sole monitoring method. In a previous study, we retrospectively evaluated the variables associated with scintigraphic success. Ablation dose (AD) was the only variable associated with success (odds ratio (OR): 1.96 per 1.85 GBq increment; 95% confidence interval (CI)=1.11-3.46). OBJECTIVES: (1) To determine if the variables associated with success are the same using Tg. (2) To determine whether Tg measurement can become the sole method for assessing ablation success. METHODS: We performed the analysis using a Tg level |
| Databáze: | OpenAIRE |
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