Platelet-rich plasma to rescue an ulcerated orbital dermal fat graft
| Autor: | Roberto Secondi, Alberto Luis Díaz Díaz, Juan Carlos Sánchez España, Tania Andrea Chaparro Tapias, Helena Coy Villamil |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Prosthesis Implantation 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine medicine Orbital Diseases Humans Autografts Ulcer Aged business.industry Platelet-Rich Plasma General Medicine Middle Aged Surgery Ophthalmology Adipose Tissue Platelet-rich plasma 030221 ophthalmology & optometry Blood supply Female Implant Complication business Orbital Implants |
| Zdroj: | European journal of ophthalmology. 29(6) |
| ISSN: | 1724-6016 |
| Popis: | Introduction: Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft. Methods: Three patients, who had undergone autologous dermal fat graft to treat their anophthalmic socket, were given a 2-mL subconjunctival platelet-rich plasma injection in the exposed graft margins. Demographic and clinical features, treatment protocol, clinical course, complications and follow-up time are reported. In the preoperative examination, all the patients presented a primary epithelial defect of the dermal fat graft. Results: There were no major complications such as necrosis or infection. One patient presented a small conjunctival granuloma at 1-month follow up. Mean postoperative follow-up duration was 13 (range: 10–16) months. By 1 month, the chronic epithelial defect had resolved with the graft integrated within the orbital tissues in all cases. All patients were referred for artificial prosthesis placement. Conclusion: Although further work is needed, our findings suggest that a single subconjunctival platelet-rich plasma injection could be an effective, safe and economic alternative to surgery to rescue an ulcerated orbital dermal fat graft. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|