BIOCHEMICAL STUDIES OF AN UNNATURAL AND ANTITUMOR AMINO ACID: 1-AMINOCYCLOPENTANECARBOXYLIC ACID: II. EFFECTS ON CELLULAR RESPIRATION AND AMINO ACID METABOLISM

Autor:	L. M. Babineau, R. O. Laferté, Nicole Bégin, Louis Berlinguet
Rok vydání:	1962
Předmět:	chemistry.chemical_classification Cycloleucine Cellular respiration Stereochemistry Transamination General Medicine Metabolism Amino acid chemistry.chemical_compound chemistry Biochemistry Reactivity (chemistry) Amino acid metabolism Aminocyclopentanecarboxylic Acid
Zdroj:	Canadian Journal of Biochemistry and Physiology. 40:433-436
ISSN:	0576-5544
DOI:	10.1139/o62-049
Popis:	1-Aminocyclopentanecarboxylic acid (ACPC) was studied for its effect on cellular respiration of rat tissues and for its reactivity towards decarboxylases, transaminases, and amino acid oxidases. In the tissues studied, cellular respiration was normal. The amino acid was not decarboxylated, transaminated, or oxidized. The transamination and oxidation of other amino acids remained normal even in the presence of ACPC.Using the radioactive substance, it was found that the molecule remains intact within the cells since no metabolic products could be detected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4bcb56dd44c443bdbae331a5368355 https://doi.org/10.1139/o62-049 Zobrazit plný text záznamu