| Popis: |
Promitochondria of anaerobically grown Saccharomyces cerevisiae lack cytochromes aa 3 , b, c 1 , and c , as well as ubiquinone, yet catalyze a P i -ATP exchange reaction that is sensitive to uncouplers, rutamycin, and atractyloside. The promitochondrial P i -ATP exchange reaction is abolished by the cytoplasmic “petite” mutation, as well as by growth of the cells in the presence of erythromycin, which indicates a role of mitochondrial protein synthesis in the assembly of the energy transfer system. These observations demonstrate that mitochondrial energy transfer can occur in the absence of a respiratory chain. |
