Supplementary Data from Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition
| Autor: | Roderick Dashwood, Eduardo Vilar, Kyle Chang, Mark Bedford, Emily Ho, Laura Beaver, David Lieberman, Hon-Chiu Leung, Shan Wang, Yun Huang, Deqiang Sun, Jia Li, Mutian Zhang, Furkan Ertem, Ahmet Ulusan, Nhung Nguyen, Mohaiza Dashwood, Ying-Shiuan Chen, Li Li, Gavin Johnson, Praveen Rajendran |
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| Rok vydání: | 2023 |
| DOI: | 10.1158/0008-5472.22423092 |
| Popis: | Fig S1 shows HDAC3 knockdown, Fig S2 shows CCAR2 acetylation in SW480 colon cancer cells. Fig S3 shows mass spectrometry data, Fig S4 shows acetylation mutant data, Fig S5 shows a Working model, Fig S6 shows genetically encoded acetylation data, Fig S7 shows in silico docking, Fig S8 shows apoptosis by SFN+JQ1, Fig S9 shows CCAR2/β-catenin interaction in human polyps, and Fig S10 shows ChIP data in cells. |
| Databáze: | OpenAIRE |
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