Pine nanocellulose and bacterial nanocellulose dressings are similar in the treatment of second-degree burn?: experimental study in rats
| Autor: | Washington Luiz Esteves Magalhães, Maria Angelica Baron Magalhães, F. C. Claro, Alysson Matioski, Guilherme Andrade Coelho, Jurandir Marcondes Ribas-Filho, Osvaldo Malafaia, Thayline Mylena Santana de Camargo, Rafael Koerich Ramos |
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| Přispěvatelé: | Guilherme Andrade Coelho, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, Maria Angélica Baron Magalhães, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, Alysson Matioski, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, Jurandir Marcondes Ribas-Filho, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF, Francine Ceccon Claro, Doutoranda da UFPR, Rafael Koerich Ramos, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, Thayline Mylena Santana de Camargo, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas, Osvaldo Malafaia, Faculdade Evangélica Mackenzie do Paraná - FEMPAR/Instituto de Pesquisas Médicas. |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
RD1-811 Dentistry Wound healing 02 engineering and technology RC799-869 Therapeutics Nanocellulose 03 medical and health sciences chemistry.chemical_compound Terapêutica 0302 clinical medicine Animals Second-Degree Burn Nanotechnology Rats Wistar Cellulose Chemistry business.industry Nanotecnologia Biomaterial 030208 emergency & critical care medicine General Medicine Diseases of the digestive system. Gastroenterology Pinus 021001 nanoscience & nanotechnology Bandages Rats Bandagem Bacterial cellulose Original Article Lower cost Surgery Collagen Cicatrização Burns 0210 nano-technology business |
| Zdroj: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA ABCD: Arquivos Brasileiros de Cirurgia Digestiva ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) v.33 n.2 2020 ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) Colégio Brasileiro de Cirurgia Digestiva (CBCD) instacron:CBCD ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), Volume: 33, Issue: 2, Article number: e1533, Published: 20 NOV 2020 Arquivos Brasileiros de Cirurgia Digestiva : ABCD |
| Popis: | Background: Despite all the advances in medicine and the wide variety of dressings available, the treatment of burn wounds still represents an important medical challenge. The pinus cellulose membrane dressing is a biomaterial with characteristics similar to those of bacterial cellulose, but with lower cost. Aim: To evaluate the efficacy of pinus nanocellulose membrane on healing of deep second degree burns in rats and compare with Membracel®. Method: Thirty male Wistar rats were submitted to deep second degree burn in dorse, with boiling water at 97o C for 20 s, generating a 314 mm² area wound. The animals were distributed in three dressing groups (n=10): group 1 - simple gauze; group 2 - bacterial cellulose membrane (Membracel®); and group 3 - pinus cellulose membrane. They were evaluated for 20 days to verify clinical condition, macro and microscopic appearance and wound contraction. Results: All of them remained clinically well with no differences in weight. Crusts were observed in group 1, and none in groups 2 and 3. Regarding to scar contraction, groups 2 and 3 were similar, better than group 1. Microscopic analysis showed predominance of advanced healing degree in groups 1 and 3, and initial in group 2. Mature collagen was predominant in all groups. Conclusion: The pinus nanocellulose membrane is effective in the treatment of experimental second degree burn in rats and its effectiveness is similar to that of the bacterial nanocellular membrane. Graphical Abstract Crusts in 7th follow-up day: G1 yes; G2 no; G3 no (left to right) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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