Retrospective analysis of opioid prescriptions in cancer patients in a northern Italian Region
| Autor: | Tom Walley, Patrizia Debetto, G. Terrazzani, Paola Zambon, Alessandro Chinellato, Stefano Guzzinati, Pietro Giusti |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Narcotics Palliative care Adolescent Administration Oral Administration Cutaneous Drug Prescriptions Fentanyl Neoplasms medicine Humans Pharmacology (medical) Registries Medical prescription Child Aged Retrospective Studies Pharmacology Morphine business.industry Palliative Care Infant Newborn Infant Original Articles Middle Aged Buprenorphine Cancer registry Italy Opioid Child Preschool Anesthesia Female Cancer pain business medicine.drug |
| Zdroj: | British Journal of Clinical Pharmacology. 62:130-133 |
| ISSN: | 1365-2125 0306-5251 |
| DOI: | 10.1111/j.1365-2125.2006.02600.x |
| Popis: | We evaluated patterns of use of opioids in palliative care across one region in Italy by cross-referencing a cancer registry with unique patient identifiers, with prescription databases. There were 90 803 patients in the registry, of whom 39 597 died during the study period. Only 8539 (21%) of these were prescribed opioids at the time of their death. Prescribed daily doses of oral morphine used (45 mg) and of buprenorphine (0.71 mg) were low compared with injected morphine (28.6 mg, equivalent to approximately 90 mg of oral morphine) and especially with doses of transdermal fentanyl (1.13 mg, equivalent to approximately 180 mg morphine). The reasons for this acceptance of transdermal fentanyl and reluctance to use oral morphine are unclear, but it seems that more effort in educating healthcare professionals and patients about the use of morphine would be useful. The use of more detailed prescribing data such as prescribed or received daily doses can add to our understanding of headline prescribing data. |
| Databáze: | OpenAIRE |
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