Uric Acid Level and New-Onset Atrial Fibrillation in the Japanese General Population ― Longitudinal Study ―
| Autor: | Satoko Ojima, Shigeho Maenohara, Shiro Yoshifuku, Mitsuru Ohishi, Takuro Kubozono, Masaaki Miyata, Hironori Miyahara, Shin Kawasoe |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Population 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound Sex Factors 0302 clinical medicine Asian People Japan Risk Factors Internal medicine Atrial Fibrillation medicine Humans Longitudinal Studies 030212 general & internal medicine Risk factor education Aged education.field_of_study Creatinine business.industry Incidence (epidemiology) Hazard ratio Age Factors General Medicine Middle Aged medicine.disease Uric Acid chemistry Cardiology Uric acid Female Cardiology and Cardiovascular Medicine business Body mass index Dyslipidemia |
| Zdroj: | Circulation Journal. 83:156-163 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-18-0508 |
| Popis: | BACKGROUND The independent role of uric acid (UA) as a risk factor for atrial fibrillation (AF) has not been fully elucidated. Methods and Results: We studied 111,566 subjects (53,416 men; 58,150 women) who underwent annual health check-ups. We divided them by sex into tertile of baseline UA. To investigate the predictive power of UA for new-onset AF, we performed Cox proportional hazard analysis including UA tertiles, body mass index, creatinine, smoking and drinking status, and presence of hypertension, diabetes, and dyslipidemia. During 4.1 years, 467 men (0.87%) and 180 women (0.31%) had AF (P |
| Databáze: | OpenAIRE |
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