An Organometallic Strategy for Assembling Atomically Precise Hybrid Nanomaterials
| Autor: | Daishi Fujita, Arnold L. Rheingold, Yanxiao Han, Petr Král, Julia M. Stauber, Elaine A. Qian, Alexander M. Spokoyny |
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| Rok vydání: | 2019 |
| Předmět: |
Spectrometry
Mass Electrospray Ionization Magnetic Resonance Spectroscopy Materials science Metal Nanoparticles Nanotechnology 010402 general chemistry 01 natural sciences Biochemistry Catalysis Article Nanomaterials Nanoclusters chemistry.chemical_compound Colloid and Surface Chemistry Organometallic Compounds Cluster (physics) Systematic synthesis Organometallic chemistry Extramural General Chemistry 0104 chemical sciences chemistry Complex protein Colloidal gold Gold Multivalent binding |
| Zdroj: | J Am Chem Soc |
| DOI: | 10.26434/chemrxiv.9783800.v1 |
| Popis: | For decades, chemists have strived to mimic the intricate design and diverse functions of naturally occurring systems through the bioinspired synthesis of programmable inorganic nanomaterials. The development of thiol-capped gold nanoparticles (AuNPs) has driven advancement in this area; however, although versatile and readily accessible, hybrid AuNPs are rarely atomically precise, which limits control over their surface topology and therefore the study of complex structure-function relationships. Here, we present a bottom-up approach to the systematic assembly of atomically precise hybrid nanoclusters employing a strategy that mimics the synthetic ease with which thiol-capped AuNPs are normally constructed, while producing welldefined covalent nanoscale assemblies with diverse surface topologies. For the first time, using a structurally characterized cluster-based organometallic building block, we demonstrate the systematic synthesis of nanoclusters with multivalent binding capabilities to complex protein targets. |
| Databáze: | OpenAIRE |
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