Tolerance design of patient-specific range QA using the DMAIC framework in proton therapy

Autor: Do Hoon Oh, Tae Hyun Kim, Dae Yong Kim, Dong Ho Shin, Ryan P. Manger, Jeong-Eun Rah, Gwe-Ya Kim
Rok vydání: 2017
Předmět:
Zdroj: Medical Physics. 45:520-528
ISSN: 0094-2405
DOI: 10.1002/mp.12721
Popis: Purpose To implement the DMAIC (Define-Measure-Analyze-Improve-Control) can be used for customizing the patient-specific QA by designing site-specific range tolerances. Methods The DMAIC framework (process flow diagram, cause and effect, Pareto chart, control chart, and capability analysis) were utilized to determine the steps that need focus for improving the patient-specific QA. The patient-specific range QA plans were selected according to seven treatment site groups, a total of 1437 cases. The process capability index, Cpm was used to guide the tolerance design of patient site-specific range. Results For prostate field, our results suggested that the patient range measurements were capable at the current tolerance level of ±1 mm in clinical proton plans. For other site-specific ranges, we analyzed that the tolerance tends to be overdesigned to insufficient process capability calculated by the patient-specific QA data. The customized tolerances were calculated for treatment sites. Control charts were constructed to simulate the patient QA time before and after the new tolerances were implemented. It is found that the total simulation QA time was decreased on average of approximately 20% after establishing new site-specific range tolerances. We simulated the financial impact of this project. The QA failure for whole process in proton therapy would lead up to approximately 30% increase in total cost. Conclusion DMAIC framework can be used to provide an effective QA by setting customized tolerances. When tolerance design is customized, the quality is reasonably balanced with time and cost demands.
Databáze: OpenAIRE
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