The effect of acetate and bicarbonate dialysis on orthostatic blood pressure regulation
| Autor: | M. D. Okusa, D. M. Landwehr |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac output Supine position Bicarbonate medicine.medical_treatment Posture Biomedical Engineering Medicine (miscellaneous) Bioengineering Blood Pressure Acetates Biomaterials Acetic acid chemistry.chemical_compound Heart Rate Renal Dialysis Internal medicine Heart rate medicine Humans Acetic Acid Aged General Medicine Middle Aged Bicarbonates medicine.anatomical_structure Blood pressure Endocrinology chemistry Vascular resistance Cardiology Female Hemodialysis |
| Zdroj: | Artificial organs. 6(4) |
| ISSN: | 0160-564X |
| Popis: | Dialysis-induced hypotension is probably due to multiple factors which reduce cardiac output and peripheral vascular resistance. That acetate, used in dialysate as a source of bicarbonate, may be one of these factors is suggested from several studies which show improved blood pressure regulation with bicarbonate-containing dialysate. We have further examined this hypothesis by comparing supine and standing blood pressure changes in nine stable patients during dialysis with acetate or bicarbonate solutions. Although mean weight changes were not different, standing blood pressure was lower after acetate dialysis. Such a hypotensive effect of acetate could result from depression of the force of myocardial contraction and/or from a reduction in peripheral vascular resistance. |
| Databáze: | OpenAIRE |
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