Glycosidic Flavonoids as Rat-Liver Injury Preventing Compounds from Green Tea
| Autor: | Shingo Wada, Naoharu Watanabe, Ikue Hashimoto, Puming He, Kimio Sugiyama |
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| Rok vydání: | 2000 |
| Předmět: |
Molecular Sequence Data
Flavonoid Galactosamine Spectrometry Mass Fast Atom Bombardment Applied Microbiology and Biotechnology Biochemistry Flavones Analytical Chemistry Flavonols medicine Animals Glycosides Trisaccharide Nuclear Magnetic Resonance Biomolecular Molecular Biology Flavonoids Liver injury chemistry.chemical_classification Organic Chemistry food and beverages Glycoside Glycosidic bond General Medicine medicine.disease Rats Carbohydrate Sequence chemistry Polyphenol Chemical and Drug Induced Liver Injury Biotechnology |
| Zdroj: | Bioscience, Biotechnology, and Biochemistry. 64:2262-2265 |
| ISSN: | 1347-6947 0916-8451 |
| DOI: | 10.1271/bbb.64.2262 |
| Popis: | A glycosidic flavonoids-rich fraction from green tea leaves was purified to isolate five glycosidic flavonoids, guided by the detection of a preventive effect on D-galactosamine-induced liver injury in rats. These were identified as a flavone C-glycoside (1) and trisaccharide flavonols (2-5) based on the spectroscopic analyses. These compounds suppressed the D-galactosamine-induced increase of plasma alanine aminotransferase and asparatate aminotransferase activities in rats. |
| Databáze: | OpenAIRE |
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