Effect on corneal endothelial cell loss during phacoemulsification: Fortified balanced salt solution versus Ringer lactate
| Autor: | Rashmi O. Shukla, Barun K. Nayak |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
Corneal endothelium medicine.medical_specialty Ringer's Lactate Senile cataract medicine.medical_treatment Cell Count Balanced salt solution Intraocular Irrigating Solution Corneal Endothelial Cell Loss Postoperative Complications Primary outcome Double-Blind Method Lens Implantation Intraocular Ophthalmology medicine Humans Prospective Studies Therapeutic Irrigation Phacoemulsification business.industry Endothelium Corneal Middle Aged Glutathione Sensory Systems Bicarbonates Drug Combinations Female Surgery Ringer lactate sense organs Isotonic Solutions Ophthalmic Solutions business |
| Zdroj: | Journal of Cataract and Refractive Surgery. 38:1552-1558 |
| ISSN: | 0886-3350 |
| DOI: | 10.1016/j.jcrs.2012.04.036 |
| Popis: | Purpose To compare the effect of phacoemulsification on the corneal endothelium using fortified balanced salt solution (BSS Plus) and Ringer lactate as the intraocular irrigating solution. Setting P.D. Hinduja Hospital, Mumbai, India. Design Prospective randomized controlled double-blinded clinical study. Methods Patients with senile cataract up to nuclear grade III were randomized to have phacoemulsification with posterior chamber intraocular lens implantation performed using fortified balanced salt solution (Group A) or Ringer lactate (Group B) as the intraocular irrigating solution. The corneal endothelial cell density (primary outcome) and pachymetry were measured preoperatively and 1 week and 1 and 6 months postoperatively. Results Each group comprised 35 eyes (35 patients). The postoperative percentage of endothelial cell loss was not significantly different between the 2 groups at 1 week ( P =.582), 1 month ( P =.668), or 6 months (5.03% and 8.35% in Group A and Group B, respectively) ( P =.483) and was within the limits reported in the literature. The postoperative percentage change in pachymetry was not significantly different between the 2 groups at 1 week ( P =.179) or 1 month ( P =.170) but was significant at 6 months ( P Conclusion Corneal endothelial cell loss after phacoemulsification with Ringer lactate was similar to that with fortified balanced salt solution over the long term. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|