IgG4-related tubulointerstitial nephritis and lymphadenopathy after therapy for malignant lymphoma
| Autor: | Naoki Hasegawa, Yukio Kakuta, Ryosuke Usui, Shun Manabe, Michiyasu Hatano, Kosaku Nitta, Yasuko Oshima |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Henoch-Schonlein purpura Prednisolone Lymph node biopsy Adrenal Cortex Hormones parasitic diseases Biopsy Internal Medicine medicine Humans Lymphatic Diseases Lymphoma Follicular medicine.diagnostic_test business.industry General Medicine equipment and supplies medicine.disease Lymphoma Immunoglobulin G Colonic Neoplasms Nephritis Interstitial IgG4-related disease Lymph business Nephritis medicine.drug |
| Zdroj: | Internal medicine (Tokyo, Japan). 51(10) |
| ISSN: | 1349-7235 |
| Popis: | We report a middle-aged Japanese man who had a past history of malignant lymphoma with tubulointerstitial nephritis (TIN) presenting a high serum immunoglobulin G4 (IgG4) concentration and bilateral kidney enlargement and swelling of many lymph nodes. Although lymph node biopsy was not evident of a recurrence of lymphoma, kidney biopsy showed prominent infiltration of IgG4-positive plasma cells in a tubulointerstitial lesion but not in glomeruli. We made a diagnosis of IgG4-related TIN and lymphadenopathy; administration of oral prednisolone improved his physical and laboratory parameters. This is the first report of a case of IgG4-related TIN and lymphadenopathy after therapy for malignant lymphoma. |
| Databáze: | OpenAIRE |
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