Quantifying the value of stroke disability outcomes: WHO global burden of disease project disability weights for each level of the modified Rankin Scale
| Autor: | Keun-Sik Hong, Jeffrey L. Saver |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Burden of disease
medicine.medical_specialty Activities of daily living Modified delphi Global Health World Health Organization Severity of Illness Index World health Article Disability Evaluation Quality of life Cost of Illness Modified Rankin Scale Surveys and Questionnaires Severity of illness Activities of Daily Living Outcome Assessment Health Care Medicine Humans Disabled Persons Stroke Advanced and Specialized Nursing Observer Variation Patient Care Team business.industry Stroke Rehabilitation Length of Stay medicine.disease Prognosis Data Interpretation Statistical Physical therapy Quality of Life Neurology (clinical) Cardiology and Cardiovascular Medicine business |
| Zdroj: | Stroke. 40(12) |
| ISSN: | 1524-4628 |
| Popis: | Background and Purpose— The modified Rankin Scale (mRS) categorizes poststroke disability among 7 broad, ordinal grades, but the interval distances between these levels are spaced along the disability spectrum have not been previously investigated. Methods— We used the person trade-off procedure developed by the World Health Organization Global Burden of Disease Project (WHO-GBDP) to generate disability weights (DWs) ranging from 0 (normal) to 1 (dead) for each of 7 mRS grades. The ratings of an international, 9-member panel of stroke experts were combined by a modified Delphi process. Results— DWs (95% CI) were 0 for mRS 0, 0.046 (0.004 to 0.088) for mRS 1, 0.212 (0.175 to 0.250) for mRS 2, 0.331 (0.292 to 0.371) for mRS 3, 0.652 (0.625 to 0.678) for mRS 4, 0.944 (0.873 to 1.015) for mRS 5, and 1.0 for mRS 6. DWs of adjacent mRS levels were significantly different ( P Conclusions— Formal DW assignment confirms that the mRS is an ordered but unequally spaced scale. The availability of DWs for each mRS level now permits direct comparison of each poststroke outcome state with the outcomes of hundreds of other diseases in the WHO-GBDP and the expression of stroke burden in different populations by using the uniform metric of disability-adjusted life-years lost. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|