Left ventricular diastolic function in end-stage renal disease and the impact of hemodialysis
| Autor: | Suresh C. Dash, M.Vijay Kumar, Sanjay Gupta, Vishva Dev |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Diastole Renal function Doppler echocardiography Ventricular Function Left End stage renal disease Nephropathy Renal Dialysis Internal medicine medicine Humans Ejection fraction medicine.diagnostic_test business.industry medicine.disease Echocardiography Doppler Cardiology Kidney Failure Chronic Female Hemodialysis Cardiology and Cardiovascular Medicine business Isovolumic relaxation time |
| Zdroj: | The American Journal of Cardiology. 71:1427-1430 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(93)90604-b |
| Popis: | Twenty-one patients (17 men and 4 women, aged 20 to 40 years) with end-stage renal disease (creatinine clearance persistently5 ml/min for3 months) were evaluated for left ventricular (LV) diastolic function by Doppler echocardiography before and after hemodialysis. Fifteen patients were on maintenance hemodialysis (group A) and 6 were studied before and after their first hemodialysis (group B). The following indexes of LV diastolic function were studied: (1) isovolumic relaxation time; and (2) Doppler indexes from mitral inflow signal--peak early velocity, peak late velocity (atrial), deceleration of early filling phase, and deceleration time of early filling phase. LV systolic function in groups A and B (LV ejection fraction 68 +/- 6 and 77 +/- 5%, fractional shortening 0.39 +/- 0.06 and 0.46 +/- 0.05%) was normal and did not change after hemodialysis. Group A had a prolonged isovolumic relaxation time of 80 +/- 22 ms, which decreased to 57 +/- 14 ms (p0.005). Deceleration time decreased from 248 +/- 58 to 184 +/- 38 ms (p0.00005) and the deceleration slope increased from 4.3 +/- 1.8 to 5.1 +/- 1.6 m/s2 (p0.005) after hemodialysis. In group B, isovolumic relaxation time decreased from 87 +/- 21 to 73 +/- 15 ms (p0.05), deceleration time decreased from 256 +/- 43 to 185 +/- 34 ms (p0.05), and deceleration slope increased from 3.5 +/- 0.8 to 4.2 +/- 1.1 m/s2 (p0.01).(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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