Prevalence of Progressive Supranuclear Palsy and Corticobasal Syndrome in Scotland
| Autor: | Carl Counsell, Diane Swallow |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Neuroepidemiology. 56:291-297 |
| ISSN: | 1423-0208 0251-5350 |
| Popis: | Introduction: We estimated the point prevalence of progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) at regional and national levels in Scotland, UK, as there are few high-quality prevalence studies of these conditions. Methods: Nationally, multiple methods of case ascertainment were used including clinician and nurse specialist referral, searches of ICD-10 diagnostic coding in routinely collected electronic health data (Scottish Morbidity Record), and patient self-referral. In one region, we also searched GP databases and unselected hospital correspondence. Cases were verified by clinical examination or medical record review. National and regional total and age-sex-stratified crude prevalence rates on December 31, 2018, were calculated. Results: The regional crude point prevalence was 4.28 per 100,000 (95% CI 2.90, 6.31) for PSP and 2.05 per 100,000 (95% CI 1.17, 3.59) for CBS. The national crude prevalence rates were lower due to the greater reliance on passive case ascertainment. There were no clear sex differences. At a national level, the peak crude prevalence rate for both PSP and CBS was in the 70–79 age group. Discussion: The prevalence rates of PSP and CBS were similar to previous estimates with little change over the past 20 years. |
| Databáze: | OpenAIRE |
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