Manometric abnormalities of the oesophagus in patients with Parkinson's disease
| Autor: | A. Colcher, Donald O. Castell, June A. Castell, Qun Li, R M Gideon, Brian T. Johnston |
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| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease Motor dysfunction Oesophageal manometry Physiology Manometry Gastroenterology Esophagus Disease severity Internal medicine otorhinolaryngologic diseases medicine Humans In patient Myenteric plexus Aged Aged 80 and over Endocrine and Autonomic Systems business.industry Parkinson Disease Middle Aged medicine.disease Dysphagia Esophageal Spasm Diffuse Dorsal motor nucleus Female Peristalsis Esophagogastric Junction medicine.symptom business |
| Zdroj: | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 13(4) |
| ISSN: | 1350-1925 |
| Popis: | Dysphagia in Parkinson’s disease (PD) is known to correlate with abnormalities of oropharyngeal function. Oesophageal abnormalities have not been previously demonstrated to correlate with dysphagia. The aim of the study was to determine if motor dysfunction of the oesophageal body correlates with dysphagia or disease severity in PD. Twenty-two patients with PD were assessed for the severity of their dysphagia (scale of 1–7) and severity of PD (Hoehn and Yahr scale 1–4). All underwent oesophageal manometry. Dysphagia was present daily in 10 patients (45%). Parkinson’s disease was graded as severe (Hoehn and Yahr >=3) in eight (36%) patients. Oesophageal manometry was abnormal in 16 (73%) patients. Thirteen patients had either complete aperistalsis or multiple simultaneous contractions (diffuse oesophageal spasm). These findings were significantly more common in patients with daily dysphagia (90% vs. 33%; P |
| Databáze: | OpenAIRE |
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