Assessing Measles Vaccine Failure in Tianjin, China
| Autor: | Matthew L. Boulton, Yaxing Ding, Nina B. Masters, Ying Zhang, Abram L. Wagner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty China Vaccination Coverage Adolescent 030231 tropical medicine Measles Vaccine Measles Article Disease Outbreaks 03 medical and health sciences Young Adult 0302 clinical medicine medicine Humans 030212 general & internal medicine Treatment Failure Child Immunization Schedule Measles elimination Disease surveillance General Veterinary General Immunology and Microbiology business.industry Public Health Environmental and Occupational Health Infant medicine.disease Vaccination Infectious Diseases Vaccination coverage Case-Control Studies Child Preschool Epidemiological Monitoring Molecular Medicine Female Measles vaccine business Vaccine failure |
| Zdroj: | Vaccine |
| Popis: | Despite increasing global measles vaccination coverage, progress toward measles elimination has slowed in recent years. In China, children receive a measles-containing vaccine (MCV) at 8 months, 18–24 months, and some urban areas offer a third dose at age 4–6 years. However, substantial measles cases in Tianjin, China, occur among individuals who have received multiple MCV doses. This study describes the vaccination history of measles cases 8 months – 19 years old. Data came from measles cases in Tianjin’s reportable disease surveillance system (2009–2013), and from a case control study (2011–2015). Twenty-nine percent of those in the surveillance dataset and 54.4% of those in the case series received at least one dose of MCV. The minimum and median time-to-diagnosis since vaccination revealed an increase in time since vaccination for incremental doses. Considerable measles cases in Tianjin occur in vaccinated children, and further research is needed to understand the reasons for vaccine failure. |
| Databáze: | OpenAIRE |
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