A note on a stochastic model for the incubation of transfusion- associated AIDS

Autor: J. Gani
Rok vydání: 1991
Předmět:
Zdroj: Discrete Mathematics. 92:89-94
ISSN: 0012-365X
Popis: The model-based approach of Lui, Peterman, Lawrence and Allen (1988) to the transfusion- associated incubation period of AIDS, and the mechanism of HIV infectivity outlined by Margolick, Bowen, Lane and Fauci (1986), and Fauci (1988), suggest that a stochastic process may account for the depletion of the T-lymphocytes before AIDS symptoms aredetected. This paper considers a simple death process as an example. After estimating the relevant parameters, the fit of this process to the given data proves to be satisfactory.
Databáze: OpenAIRE