Gene modulation in total brain induced by exposure to the bicyclic phosphorus ester trimethylolpropane phosphate (TMPP)

Autor:	T.T. Mann, Joseph J. Pancrazio, John Rossi, Joanne D. Andreadis, David A. Stenger, Glenn D. Ritchie, M. Y.-V. Bekkedal, A.C. Russell
Rok vydání:	2002
Předmět:	Therapeutic gene modulation Regulation of gene expression Brain Chemistry Male Reverse Transcriptase Polymerase Chain Reaction General Neuroscience GABA receptor antagonist Biology Toxicology Bridged Bicyclo Compounds Heterocyclic Epileptogenesis Molecular biology Rats Rats Sprague-Dawley medicine.anatomical_structure Biochemistry Gene Expression Regulation Complementary DNA Gene expression Convulsant medicine Animals Environmental Pollutants Sensitization Oligonucleotide Array Sequence Analysis
Zdroj:	Neurotoxicology. 23(2)
ISSN:	0161-813X
Popis:	The effect of a single subconvulsive dose of the GABAergic convulsant trimethylolpropane phosphate (TMPP) on gene expression in total rat brain was examined using cDNA array analysis. Using threshold criteria that reduce the number of false positives to
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df9d6cf0fab9e60b88558dd17df9529 https://pubmed.ncbi.nlm.nih.gov/12224763 Zobrazit plný text záznamu Full Text from ScienceDirect