Prostate-Specific Membrane Antigen–Guided Surgery

Autor: Freddie C. Hamdy, Tobias Maurer, Matthias Eiber, Fijs W. B. van Leeuwen, Markus Graefen, Henk G. van der Poel, Alberto Briganti, Hans-Jürgen Wester
Přispěvatelé: Maurer, T., Graefen, M., van der Poel, H., Hamdy, F., Briganti, A., Eiber, M., Wester, H. -J., van Leeuwen, F. W. B.
Rok vydání: 2019
Předmět:
Male
Proteasome Endopeptidase Complex
medicine.medical_specialty
image-guided surgery
Urology
030232 urology & nephrology
lymph node dissection
Lymph node dissection
Ligands
Medical Oncology
Radiosurgery
urologic and male genital diseases
Fluorescence
03 medical and health sciences
Prostate cancer
0302 clinical medicine
salvage
medicine
Glutamate carboxypeptidase II
Image-guided surgery
Humans
Radiology
Nuclear Medicine and imaging
Lymph node
Membrane antigen
Salvage Therapy
business.industry
Prostatic Neoplasms
Technetium
Therapeutic decision making
prostate cancer
medicine.disease
Surgery
Dissection
medicine.anatomical_structure
Surgery
Computer-Assisted
Lymphatic Metastasis
Positron-Emission Tomography
030220 oncology & carcinogenesis
Salvage
Lymph Node Excision
Recurrent prostate cancer
fluorescence
Neoplasm Recurrence
Local
Radiopharmaceuticals
business
Zdroj: Journal of Nuclear Medicine, 61(1), 6-12. SOC NUCLEAR MEDICINE INC
ISSN: 2159-662X
0161-5505
Popis: Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)–ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.
Databáze: OpenAIRE
Externí odkaz: