'ZSTATS'--a statistical analysis for potential Z-DNA sequences
| Autor: | J K Vass, R H Wilson |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Computational biology Biology DNA sequencing Z-DNA chemistry.chemical_compound Microcomputers Pregnancy Genetics Methods Humans Statistical analysis Base sequence Globin Base Composition Base Sequence Computers DNA Embryo Mammalian Globins chemistry Biological significance Nucleic Acid Conformation Female Software |
| Zdroj: | Nucleic acids research. 12(1 Pt 2) |
| ISSN: | 0305-1048 |
| Popis: | We have developed a FORTRAN programme for scanning DNA sequences for potential Z-DNA forming regions using the One-Sample Runs Test. The programme also detects other non-random arrangements of purines and pyrimidines on the same strand and will detect purine- or pyrimidine-rich strands and G:C- or A:T-rich regions. A series of test statistics are produced as a graphical output and these have been used to search a number of beta- type globin DNA sequences for potential Z-DNA regions whose biological significance is briefly discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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