Neural breathing pattern in newborn infants pre- and postextubation
| Autor: | Michelle E. Ruiz, Ricardo J. Rodriguez, Chister Sinderby, Robert L. Chatburn, Narayan P. Iyer, Jennifer Beck, John M. Dickson |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Extubation failure business.industry Respiration Diaphragm Infant Newborn 030208 emergency & critical care medicine General Medicine Diaphragm (structural system) 03 medical and health sciences 0302 clinical medicine Breathing pattern Control of respiration 030225 pediatrics Anesthesia Pediatrics Perinatology and Child Health Airway Extubation Neurally adjusted ventilatory assist Humans Infant Very Low Birth Weight Medicine Female Prospective Studies business |
| Zdroj: | Acta Paediatrica. 106:1928-1933 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/apa.14040 |
| Popis: | Aim To describe the neural breathing pattern before and after extubation in newborn infants. Methods Prospective, observational study. In infants deemed ready for extubation, the diaphragm electrical activity (EAdi) was continuously recorded from 30 minute before to 2 hours after extubation. Results Total of 25 neonates underwent 29 extubations; 10 extubations resulted in re-intubation within 72 hours. Postextubation, there was an increase in peak EAdi (EAdi-max) and EAdi delta (peak minus minimum EAdi) in both groups. The pre to post extubation change in EAdi-max (8.9 to 11.1 μv) and EAdi-delta (6 to 8 μv) was less in the failure group in comparison to the change in EAdi-max (10.2 to 13.4 μv) and EAdi delta (6.3 to 10.6 μv) in the success group, (p= 0.02 and 0.01 respectively). Conclusion In our neonatal cohort, extubation failure was associated with a smaller increase in peak and delta EAdi after extubation. If confirmed, these findings indicate an important cause of extubation failure in preterm infants. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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