Bailout left atrial appendage occluder for pulmonary vein isolation and electrical cardioversion in patients with atrial fibrillation and left atrial appendage thrombus: a pilot study

Autor: Chin-Feng Tsai, Pang-Shuo Huang, Fu-Chun Chiu, Jien-Jiun Chen, Sheng-Nan Chang, Jung-Cheng Hsu, Su-Kiat Chua, Hsiao-Liang Cheng, Yi-Chih Wang, Juey-Jen Hwang, Chia-Ti Tsai
Rok vydání: 2022
Předmět:
Zdroj: Clinical research in cardiology : official journal of the German Cardiac Society.
ISSN: 1861-0692
Popis: Cardioversion and catheter-based circumferential pulmonary vein isolation (CPVI) are established rhythm control treatment strategies for patients with atrial fibrillation (AF). However, these treatments are contraindicated for AF patients with a left atrial appendage (LAA) thrombus.We conducted the first-in-man case series study to evaluate the feasibility and safety of performing cardioversion or CPVI in AF patients with LAA thrombus immediately after implantation of LAA Occluder (LAAO) in a combined procedure. In our multi-center LAAO registry of 310 patients, 27 symptomatic and drug-refractory AF patients underwent a combined procedure of LAAO and CPVI, among whom 10 (mean age 68 ± 16 years, 6 men) having anticoagulant-resistant LAA thrombus received a bailout procedure of LAAO implantation first then CPVI, and the other 17 patients without LAA thrombus received CPVI first then LAAO for comparison.The mean CHAWe demonstrated that cardioversion or CPVI is doable in symptomatic AF patients with LAA thrombus if LAA was occluded ahead as a bailout procedure.
Databáze: OpenAIRE