Bone reconstruction: Au nanocomposite bioglasses with antibacterial properties
| Autor: | Stefania Grandi, Marcello Imbriani, Carla Renata Arciola, Enrica Saino, Piercarlo Mustarelli, Livia Visai, Marcella Bini, Valentina Cassinelli |
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| Přispěvatelé: | Grandi, S, Cassinelli, V, Bini, M, Saino, E, Mustarelli, P, Arciola, C, Imbriani, M, Visai, L, Grandi S., Cassinelli V., Bini M., Saino E., Mustarelli P., Arciola CR, Imbriani M., Visai L |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Ceramics
Staphylococcus aureus Materials science Surface Properties ANTIBACTERIAL ACTIVITY Biomedical Engineering Metal Nanoparticles Medicine (miscellaneous) Scaffolds bones Bioengineering Nanotechnology Nanocomposites Biomaterials Coated Materials Biocompatible Escherichia coli Ceramic Antibacterial agent Sol-gel Nanocomposite SOL-GEL Dopant Doping technology industry and agriculture General Medicine Anti-Bacterial Agents Chemical engineering Colloidal gold visual_art Bone Substitutes GOLD NANOPARTICLES visual_art.visual_art_medium Gold Antibacterial activity BIOGLASS |
| Popis: | Bioglasses are of wide interest since they spontaneously bond and integrate with living bone in the body. By varying the glass chemistry and/or by adding some dopants, it is possible to improve their clinical applications. Gold nanoparticles (Au NPs) are a well-known antibacterial agent, as well as a unique probe for sensing and imaging applications. We report on the synthesis of a 58S bioglass doped with Au NPs at two doping levels: 0.1% wt. and 1% wt. Antibacterial properties were observed on the Gram-positive Staphylococcus aureus, whereas no significant effects were found on the Gram-negative Escherichia coli. A possible mechanism of action of Au NPs towards bacteria has been described. |
| Databáze: | OpenAIRE |
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