8-Methoxypsoralen and the eye

Autor: Hugh Zachariae, Jørgen Marqversen, Eivind Nielsen, Ingrid Axelsen
Rok vydání: 1981
Předmět:
Zdroj: Archives of Dermatological Research. 270:387-390
ISSN: 1432-069X
0340-3696
DOI: 10.1007/bf00403782
Popis: The kinetics of migration of radiolabeled 8-methoxypsoralen into human cataract lenses were investigated in 12 patients undergoing operation. Lenses were examined from 2.5 - 72 h after intake of 3H-labeled 8-methoxypsoralen by mouth. Demonstrable amounts of activity was only found in two of three lenses studied 24 h after intake. The aqueous humor contained less 8-methoxypsoralen than serum. The results of the study may add support to the opinion that a less rigorous sunglass regimen than that recommended by certain PUVA centers may be justified.
Databáze: OpenAIRE
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