A Brief Review of the Ah Locus
| Autor: | Alan Poland, Christopher A. Bradfield |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Genetics
Polymorphism Genetic Cytochrome Hydrocarbons Halogenated Receptors Drug Chromosome Mapping Locus (genetics) General Medicine Biology AH Receptor General Biochemistry Genetics and Molecular Biology Cytochrome P-450 Enzyme System Receptors Aryl Hydrocarbon Inbred strain biology.protein Animals Polycyclic Compounds Transcriptional Activator Functional polymorphism |
| Zdroj: | The Tohoku Journal of Experimental Medicine. 168:83-87 |
| ISSN: | 1349-3329 0040-8727 |
| DOI: | 10.1620/tjem.168.83 |
| Popis: | POLAND, A, and BRADFIELD, C. A Brief Review of the Ah Locus. Tohoku J. Exp. Med., 1992, 168 (2), 83-87 - The Ah locus, first described as a functional polymorphism among inbred strains of mice, encodes the Ah receptor-a ligand dependent transcriptional activator. This paper reviews the work on the Ah receptor and its importance in the expression of cytochrome P-450IA1 and the pleiotropic effects of halogenated aromatic hydrocarbons. - Ah locus; Ah receptor; cytochrome P-450IA1; halogeneted aromatic hydrocarbons |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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