Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect
| Autor: | Richi Nakatake, Masaki Kaibori, Chika Miyasaka, Morihiko Ishizaki, Kosuke Matsui |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Hepatocellular carcinoma medicine.medical_treatment ICG indocyanine green Partial hepatectomy GSA-Rmax maximal removal rate of 99mTc-GSA S segment Article 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Resectable Hepatocellular Carcinoma medicine ICGR15 indocyanine green retention rate at 15 min GSA-RL GSA-Rmax in the predicted residual liver medicine.diagnostic_test Liver resection business.industry (PET)-CT positron emission tomography HH15 heart uptake ratio Constitutional indocyanine green excretory defect medicine.disease LHL15 liver scintigraphy CT computed tomography CP Child–Pugh chemistry Excretory system 030220 oncology & carcinogenesis Liver scintigraphy 030211 gastroenterology & hepatology Surgery GSA 99mTc-galactosyl human serum albumin Radiology Hepatectomy Liver function tests business HCC hepatocellular carcinoma 99mTc-galactosyl human serum albumin (GSA) Indocyanine green |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • Constitutional indocyanine green excretory defect is extremely rare. • The ICGR15 is important for estimating hepatic functional reserve and selection of the appropriate surgical procedure. • Because of the rarity of constitutional ICG excretory defect, its clinical features are not well understood. • At present, the indications for surgery for this condition should be comprehensively considered. • Findings of liver function tests, such as a general liver function test and GSA liver scintigraphy, are important for treating this disorder. Introduction: Constitutional indocyanine green (ICG) excretory defect is extremely rare. The indocyanine green retention rate at15 min (ICGR15) is important for estimating hepatic functional reserve and selection of the appropriate surgical procedure before hepatectomy is performed. Because of the rarity of constitutional ICG excretory defect, its clinical features are not well understood. We report here evaluation and treatment of a patient with such a disorder. Presentation of case: An 83-year-old man was admitted to hospital with the diagnosis of resectable hepatocellular carcinoma. The preoperative indocyanine green (ICG) retention rate at 15 min was greater than 76.2%. Despite this finding, Child–Pugh classification and 99mTc-galactosyl human serum albumin (GSA) liver scintigraphy didn’t show any abnormal findings, and there was no background disease. Therefore, we diagnosed him with constitutional ICG excretory defect and performed partial hepatectomy. For patients requiring hepatectomy with this disease the indications and procedure for surgery should be considered. These should be based on liver function tests such as GSA liver scintigraphy. Conclusions: Constitutional ICG excretory defect is an extremely rare disorder. At present, the indications for surgery for this condition should be comprehensively considered. Findings of liver function tests, such as a general liver function test and GSA liver scintigraphy, are important for treating this disorder. |
| Databáze: | OpenAIRE |
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